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First, find out how many magazines or newspapers are printed and how often. Be careful to get the amount printed and

According to USFDA, a combination product is one composed of any combination of a drug and device; biological product and device; drug and biological product

not the estimated readership. Most publications use a three times (3x) the printed amount when quoting their readersh

; or drug, device, and biological product and fixed dose combination would include two or more combinations of drug.

Examples of combination products may in

ip. This is used because it sounds better, plus most publications quote a 3x national average, which could or could n

lude drug-coated devices, drugs packaged with delivery devices in medical kits, and drugs and devices packaged separately but intended to be used together.

ot be true. Some publications may only get one or no reader per publication, and others may get many more. The amoun

here is enormous increase in the number of combination products entering the market in the recent years. Combination products have proven advantages but fixe

t is usually based on how popular the publication is. If a reader enjoys the publication, and there is important info

d dose combinations are still in the process of convincing regulatory authority on their advantages over the single ingredient formulations.

Combination pro

mation about topics of interest, they’ll either save it or pass it onto others to read, who in turn will do the same.

ucts have become life saving products for the pharmaceutical companies who doesn’t have many innovative molecules in their product pipeline and have been inc

The next thing to consider is how many aren’t picked up before the next edition hits the racks. Many publications wi

easingly used in the product life cycle management. Even the companies having product patents are trying to extend their product life cycle through the combi

ll print large amounts, just to have a large number to quote, but by the time the next edition is distributed, as many

nation products and maximize the revenues. But the companies involved in this practice are overlooking that they are burdening the patients both economically

as 50%, or more, of them haven’t been picked up. Publications that monitor locations and adjust their distribution a

and physically. They need to rightly judge the benefits of the combination products and they have to even look at the risks involved when combining the produ

mounts will have a smaller recycle rate. Even though they may print fewer copies, more people could be reading their

ts. Some of the combination products were well accepted by physicians while others suffered. Companies involved in development of combination products are fi

ublication over their competitors.

Ask the publication for a listing of locations near you and find out when they dis

ding difficulty in defining their combination products and facing various challenges from selecting a combination to marketing it.

Following aspects would a

tribute to these locations. Go by a few of the locations a week after they are distributed to see how many are being

dd to the challenges in developing combination products:

Which markets to tap where the combination products can do fairly well?
Which combination prod

placed in each of the chosen locations. Then, after another two weeks, stop by again to see how many of the publicati

cts are meaningful and rational?
Which therapeutic categories to select?
Which Combinations can address unmet needs of the patients?
Do combin

ons are still on the racks. This should give you a good idea of the correct recycle rates. One more thing you should

tions increase the patient compliance?
What would be the developing cost?
How to tackle the risks encountered during combination product developmen

look for. Are the publications in racks unbound so that it appears time and pride are involved in placement? Also,

t?

As combination products don't fit into the traditional categories of drugs, medical devices, or biological products, the USFDA is in the process of devel

f the publication is on a counter or table, rather than in racks, usually means the business locations of distribution

ping new procedures for reviewing their safety, efficacy and quality.

Professional from academic institutions, pharmaceutical industries, health care indust

themselves like the publication and are willing to give it better exposure.

The last thing you must consider is the

y and representatives from various regulatory agencies are working out to design the regulatory requirements for manufacture and sale of combination products

demographics and placement of the area of distribution. Be sure that the publication is in locations that match the d

.

As there is an increasing trend of the combination products companies manufacturing such products should be able to tackle the problems involved in the de

emographics you are trying to advertise to. For example, if you are trying to reach people that are 50 and over, you

elopment. They need to be wiser in analyzing the market trends and the regulatory requirements.

Companies that provide selfless information through particip

wouldn’t want to be paying to have magazines placed in a college town bar & grill that caters only to college students

tion in industry events and feedback to regulatory authorities would be able to face the challenges and will be successful in developing combination products

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With medical billing and the electronic submission of claims, just sending the claims isn't enough. They have to be sent in just the right order. In this installment, we discuss the complex topic of records hierarchy.

Every conversation is an important link in the chain toward individual and organizational success. The more effective you can be in any conversation, the more effective you will be as a leader. By paying attention to how you show up to a conversation and how you leave it, you become better equipped for success.

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