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  • E-Folder - Internet Radio Broadcasting - About Bitrates

    Streaming live audio involves using bitrates. What are bitrates? Bitrate is the bandwidth used to send a str
    According to USFDA, a combination product is one composed of any combination of a drug and device; biological product and device; drug and biological product
    eam to the listener. If you are going to broadcast via the internet you must choose a bitrate to send the co
    ; or drug, device, and biological product and fixed dose combination would include two or more combinations of drug.

    Examples of combination products may in
    tent to the listener. When choosing bitrate you must take into consideration your target audience. Will my l
    lude drug-coated devices, drugs packaged with delivery devices in medical kits, and drugs and devices packaged separately but intended to be used together.

    steners be using a broadband connection such as dsl or cable, or will they be using a dial up connection.

    S
    here is enormous increase in the number of combination products entering the market in the recent years. Combination products have proven advantages but fixe
    treaming at a bitrate higher than the listener can download results in buffering. This basically means the s
    d dose combinations are still in the process of convincing regulatory authority on their advantages over the single ingredient formulations.

    Combination pro
    ream is stopped while the listeners player downloads enough of the stream to resume playing. Obviously the
    ucts have become life saving products for the pharmaceutical companies who doesn’t have many innovative molecules in their product pipeline and have been inc
    istener will not want to continue listening to the stream if he has to wait 30 seconds or so in the middle o
    easingly used in the product life cycle management. Even the companies having product patents are trying to extend their product life cycle through the combi
    f a song.

    Generally a dial up listener can listen to a stream that broadcasts between 8kbs and 32kbs withou
    nation products and maximize the revenues. But the companies involved in this practice are overlooking that they are burdening the patients both economically
    experiencing buffering depending on the individual listeners connection. Dial up modems can accomodate a ma
    and physically. They need to rightly judge the benefits of the combination products and they have to even look at the risks involved when combining the produ
    imum band width of 56k although the actual bitrate can vary from 21k to around 52k dependant on the phone li
    ts. Some of the combination products were well accepted by physicians while others suffered. Companies involved in development of combination products are fi
    e.

    Broadband listeners can listen to audio streams at a much higher bitrate. The highest bitrate recommende
    ding difficulty in defining their combination products and facing various challenges from selecting a combination to marketing it.

    Following aspects would a
    d to stream music to broadband listeners is 128kbs. Why? Music cd's are recorded at 128kbs. Any streaming ab
    dd to the challenges in developing combination products:

    Which markets to tap where the combination products can do fairly well?
    Which combination prod
    ve this bitrate is just a waste of your bandwidth. Of course you can choose any rate between 8kbs and 128kbs
    cts are meaningful and rational?
    Which therapeutic categories to select?
    Which Combinations can address unmet needs of the patients?
    Do combin
    to stream to broadband. Rule of thumb is the higher the bitrate the better the quality of the stream althoug
    tions increase the patient compliance?
    What would be the developing cost?
    How to tackle the risks encountered during combination product developmen
    h there are several other factors to consider which I will address in my next article.

    Whats the alternativ
    t?

    As combination products don't fit into the traditional categories of drugs, medical devices, or biological products, the USFDA is in the process of devel
    if you wish to include multiple bitrates? The alternative is to get stream hosting that allows you to broad
    ping new procedures for reviewing their safety, efficacy and quality.

    Professional from academic institutions, pharmaceutical industries, health care indust
    ast at multiple bitrates. Many stream hosts offer packages that include several different bitrates to effect
    y and representatives from various regulatory agencies are working out to design the regulatory requirements for manufacture and sale of combination products
    ively let you stream to a larger audience. You send the stream from your computer to said stream server and
    .

    As there is an increasing trend of the combination products companies manufacturing such products should be able to tackle the problems involved in the de
    t sends the stream to your listeners at the multiple bitrates. You can also send your stream to multiple str
    elopment. They need to be wiser in analyzing the market trends and the regulatory requirements.

    Companies that provide selfless information through particip
    am servers if you choose in the event that one stream server fails, your stream will still be up and running


    tion in industry events and feedback to regulatory authorities would be able to face the challenges and will be successful in developing combination products

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