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There is a lot of discussion and disagreement among internet broadcaster about the bes

According to USFDA, a combination product is one composed of any combination of a drug and device; biological product and device; drug and biological product

t bitrate to use in order to get the best music quality. This article will address thi

; or drug, device, and biological product and fixed dose combination would include two or more combinations of drug.

Examples of combination products may in

s topic and the other factors that affect sound quality.

Although it is widely believ

lude drug-coated devices, drugs packaged with delivery devices in medical kits, and drugs and devices packaged separately but intended to be used together.

ed that the higher the stream bitrate the better the streaming quality there are other

here is enormous increase in the number of combination products entering the market in the recent years. Combination products have proven advantages but fixe

factors involved. One important factor is the stream encoder. There are many options

d dose combinations are still in the process of convincing regulatory authority on their advantages over the single ingredient formulations.

Combination pro

depending on what software you are using to encode your stream. For intance you could

ucts have become life saving products for the pharmaceutical companies who doesn’t have many innovative molecules in their product pipeline and have been inc

create a stream that is 128kbs stereo which sends the stream at 44khz. This would crea

easingly used in the product life cycle management. Even the companies having product patents are trying to extend their product life cycle through the combi

e a high quality broadband stream for your listeners. You can create a similar stream

nation products and maximize the revenues. But the companies involved in this practice are overlooking that they are burdening the patients both economically

at lower bitrates as well.

So why use anything other setting? Because 128kbs stereo d

and physically. They need to rightly judge the benefits of the combination products and they have to even look at the risks involved when combining the produ

oesn't necessarily give your listeners the best sound experience. In my testing a lowe

ts. Some of the combination products were well accepted by physicians while others suffered. Companies involved in development of combination products are fi

r bitrate like 64kbs encoded in mono can produce as good or better sound quality than

ding difficulty in defining their combination products and facing various challenges from selecting a combination to marketing it.

Following aspects would a

the 128kbs stereo stream. Every computer doesn't play your stream the same. On an aver

dd to the challenges in developing combination products:

Which markets to tap where the combination products can do fairly well?
Which combination prod

age computer with two speakers quite often the mono stream will be a better listening

cts are meaningful and rational?
Which therapeutic categories to select?
Which Combinations can address unmet needs of the patients?
Do combin

experience. I recently received an email from a new internet broadcaster. He wanted to

tions increase the patient compliance?
What would be the developing cost?
How to tackle the risks encountered during combination product developmen

know why my stream at 16kbs sounded better than his 64kbs stereo stream. My 16kbs stre

t?

As combination products don't fit into the traditional categories of drugs, medical devices, or biological products, the USFDA is in the process of devel

am is using mono at 16khz. It produces the best possible 16kbs listener experience in

ping new procedures for reviewing their safety, efficacy and quality.

Professional from academic institutions, pharmaceutical industries, health care indust

my opinion.

The bottom line is bigger isn't always better. If you have a broadcast st

y and representatives from various regulatory agencies are working out to design the regulatory requirements for manufacture and sale of combination products

ream experiment with differnt bitrates and encoders. Try mono and stereo. Listen to yo

.

As there is an increasing trend of the combination products companies manufacturing such products should be able to tackle the problems involved in the de

ur stream on different computers and speaker systems. Try to be the listener and exper

elopment. They need to be wiser in analyzing the market trends and the regulatory requirements.

Companies that provide selfless information through particip

ience what they will hear. This is the best way to decide on your bitrate and encoding

tion in industry events and feedback to regulatory authorities would be able to face the challenges and will be successful in developing combination products

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