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I’ve been collecting artwork since the mid-1970’s. Back then, you went to a gallery or auction and could see or touch the pieces. The dealer would answer your questions in person a

According to USFDA, a combination product is one composed of any combination of a drug and device; biological product and device; drug and biological product

nd you could view the documents or other certificates of authenticity. Today, all that has changed with the advent of the Internet. Auction sites have listings posted for almost ev

; or drug, device, and biological product and fixed dose combination would include two or more combinations of drug.

Examples of combination products may in

ery type of artwork imaginable. Ebay is the main avenue for selling art and therefore the target of most of the fraudulent dealers. I’ve seen several types of misrepresentation and

lude drug-coated devices, drugs packaged with delivery devices in medical kits, and drugs and devices packaged separately but intended to be used together.

feel I need to explain to the laymen what to watch for.

Let’s start with the obvious. If you see a Picasso that’s listed for a few dollars and the dealer claims that it has an or

here is enormous increase in the number of combination products entering the market in the recent years. Combination products have proven advantages but fixe

iginal signature, beware. Picasso’s signature alone fetches thousands of dollars. In his later years, people he dealt with would not cash his checks because the signature was worth

d dose combinations are still in the process of convincing regulatory authority on their advantages over the single ingredient formulations.

Combination pro

more than the products or services purchased. This is true for artists such as Miro, Chagall and others. If you come across a hand-signed Rembrandt print, back off completely. Rem

ucts have become life saving products for the pharmaceutical companies who doesn’t have many innovative molecules in their product pipeline and have been inc

brandt never pencil-signed his etchings as they were signed in the original etching plate. Later, Amand Durand reproduced Rembrandt’s etchings in the late 1800’s, but even he didn’

easingly used in the product life cycle management. Even the companies having product patents are trying to extend their product life cycle through the combi

t sign his prints.

Speaking of signatures, several online dealers have prints for sale that are hand-signed. You get to see the Chagall signature in a variety of crayon colors. Ye

nation products and maximize the revenues. But the companies involved in this practice are overlooking that they are burdening the patients both economically

s, they are hand-signed, but obviously not by the artist. Of course this is never stated and you, the buyer, just assumed that the signature was from the artist. And there is no CO

and physically. They need to rightly judge the benefits of the combination products and they have to even look at the risks involved when combining the produ

A or certificate of authenticity anyway. So, a word about documentation or authentication. It’s pretty easy to print up anything on a word program and even create an official-looki

ts. Some of the combination products were well accepted by physicians while others suffered. Companies involved in development of combination products are fi

g seal. So that can easily be fakes as well. So, how do you protect yourself from fraud? I would do the following before buying art from anyone on the Internet:

Look at th

ding difficulty in defining their combination products and facing various challenges from selecting a combination to marketing it.

Following aspects would a

e way the title and description is worded. Are there spelling mistakes that were made on purpose, such as “Chagal or Picaso” prints for sale?

Who is the seller? An art deal

dd to the challenges in developing combination products:

Which markets to tap where the combination products can do fairly well?
Which combination prod

er or a shoe salesman? Look at their other auctions.

Check their feedback and look at the comments. How many other pieces did they sell?

What type of COA do they p

cts are meaningful and rational?
Which therapeutic categories to select?
Which Combinations can address unmet needs of the patients?
Do combin

rovide?

Do they show a picture of what you are buying plus a close-up of the signature?

Do they offer PayPal or a credit card payment method? A cashier’s check-only

tions increase the patient compliance?
What would be the developing cost?
How to tackle the risks encountered during combination product developmen

site should tell you something.

Do they have a money-back guarantee?

Are they located in a foreign country? That could be a problem for returns.

That is

t?

As combination products don't fit into the traditional categories of drugs, medical devices, or biological products, the USFDA is in the process of devel

the short list. Before bidding, see if the piece is for sale elsewhere on the net and compare the pictures, signatures, and item descriptions like size and medium, i.e. print lith

ping new procedures for reviewing their safety, efficacy and quality.

Professional from academic institutions, pharmaceutical industries, health care indust

ograph, serigraph. They should match up. Often times you can also see the date and size of the limited edition. Do the research first. Is the same piece available for a lot less or

y and representatives from various regulatory agencies are working out to design the regulatory requirements for manufacture and sale of combination products

more elsewhere? Then something is wrong somewhere in the mix. Getting a good deal is wonderful if it’s a genuine piece. But getting something worthless for a few hundred dollars i

.

As there is an increasing trend of the combination products companies manufacturing such products should be able to tackle the problems involved in the de

s no bargain. Educate yourself and try to stay with art dealers that have been around for a while. If you suspect something fishy, move on. There are plenty of dealers out there th

elopment. They need to be wiser in analyzing the market trends and the regulatory requirements.

Companies that provide selfless information through particip

at are legitimate and offer a real product for sale. Remember that anyone can sign a piece of artwork they copied on their scanner. And anyone can buy them. Let’s hope it’s not you

tion in industry events and feedback to regulatory authorities would be able to face the challenges and will be successful in developing combination products

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Here is a list of the Top 4 don't ever do these at home or in business letter head design mistakes. Read these to make sure you don't reapeat the same mistakes that others have it can be detremental to your business credibility as well as your health.

You may know exactly how much of a comic genius Richard Pryor was, however few people are aware of what a marketing genius he was too. Here's why:

Philadelphia is the 5th largest city in the United States(US) and has been a cultural and commercial center since 18th century. It has a bustling manufacturing industry, as well as several food, retail and financial services. Starting a fitness equipment rental business in Philadelphia can be a good business idea.

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