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    In any organization, enterprise or work place there are two types of employees. One group tries to distance themselves from the powers that be, the boss. The employees in the other group try as much as they can to be recognized by the boss. A nod or smile from
    According to USFDA, a combination product is one composed of any combination of a drug and device; biological product and device; drug and biological product
    the boss sends ripples of excitement and enthusiasm down their persons.

    They paste a woebegone sulk on their faces when not recognized or when something is not done about the suggestions they put across in the last meeting. When we talk of being recognized i
    ; or drug, device, and biological product and fixed dose combination would include two or more combinations of drug.

    Examples of combination products may in
    t is not just by any Tom, Dick and Harry but by, as they put it, ‘the ones who matter’.

    Employees of this strain and nature are so rife in our work places, in Africa and the world over. In Dar es Salaam, Tanzania, for instance, such kind of employees would be
    lude drug-coated devices, drugs packaged with delivery devices in medical kits, and drugs and devices packaged separately but intended to be used together.

    called ‘wanaojifagilia’ {those who seek favours by trying to prove how expedient they are}.

    Their joy is full when they stand out in the crowd of employees and their names mentioned fondly over coffee by the bosses. That’s where their efforts gravitate towar
    here is enormous increase in the number of combination products entering the market in the recent years. Combination products have proven advantages but fixe
    ds.

    Take for instance, in most organizations and workplaces there are eight stipulated working hours. Our do-gooders will put in an extra hour ‘finishing some piece of work’ or ‘writing that report needed on the MD’s desk by Friday evening’ or something as fa
    d dose combinations are still in the process of convincing regulatory authority on their advantages over the single ingredient formulations.

    Combination pro
    r-fetched as, say, ‘photocopying all the documents in my department. Anything may happen, you know’.

    Their clever pretexts are camouflaged in ostentatious amounts of hard work. Their aim is nothing more than to show that they are hard workers. That’s their tr
    ucts have become life saving products for the pharmaceutical companies who doesn’t have many innovative molecules in their product pipeline and have been inc
    ump card.

    ‘If only you had the commitment shown by so and so…’ becomes a crystallized phrase used by the boss in meetings. Their output becomes the yard stick by which fellow workers’ efforts are judged.

    They tend to tip the balance of the management’s decis
    easingly used in the product life cycle management. Even the companies having product patents are trying to extend their product life cycle through the combi
    ion to their own favour; they have proved they are committed and can ‘deliver the goods’.

    Some employees will cash in on this situation. To gain a firmer grip on the manager’s confidence, they gradually start reporting on fellow workers’ escapades and ‘behavi
    nation products and maximize the revenues. But the companies involved in this practice are overlooking that they are burdening the patients both economically
    our’ at the workplace.

    These may range from comments about the boss to the quality of the tea and writing paper to the ‘horrible’ salary scales. Practically anything that would guarantee their sail into the boss’ good books would do for them.

    Things start ha
    and physically. They need to rightly judge the benefits of the combination products and they have to even look at the risks involved when combining the produ
    ppening. People are demoted, some fired, and memos start flying onto virtually every desk. Anyone who ‘inadvertently yawns’ in the presence of the self- conscripted mole feels the heat.

    Some guys I talked to are of the opinion that people who curry favour wit
    ts. Some of the combination products were well accepted by physicians while others suffered. Companies involved in development of combination products are fi
    h their managers have so much they are hiding under the fa?ade of working hard. Some people do as little as possible, when not being watched, because they are lazy and do not think they are paid enough. Some work hard only when they are being watched. Some com
    ding difficulty in defining their combination products and facing various challenges from selecting a combination to marketing it.

    Following aspects would a
    plain endlessly about the conditions of work or have mean attitudes towards their bosses.

    Fellow workers who get wind of the goings-on nurture an acrimonious attitude against such colleagues. Unity at the work place is sacrificed on the altar of indifference.
    dd to the challenges in developing combination products:

    Which markets to tap where the combination products can do fairly well?
    Which combination prod


    This portends a devastating end in the long term. Work output fluctuates and employees turnover inconsistency has a stem rollers effect on their morale and potential.

    The status quo should be remedied before things get out of hand. For any organization to s
    cts are meaningful and rational?
    Which therapeutic categories to select?
    Which Combinations can address unmet needs of the patients?
    Do combin
    ucceed then, the leaders and followers{read employees} are to follow certain ethics that will guarantee corporate satisfaction.

    Leaders are created, shaped and highly dependent on their followers. The two are not isolated entities; they exist in a mutual, rec
    tions increase the patient compliance?
    What would be the developing cost?
    How to tackle the risks encountered during combination product developmen
    iprocal relationship by which each moulds, shapes and gives rise to the other.

    The frontline worker is accountable. The executive VP occupies a followership role to the CEO and the CEO is in a followership position to the board of directors. Even exemplary le
    t?

    As combination products don't fit into the traditional categories of drugs, medical devices, or biological products, the USFDA is in the process of devel
    aders, at times, must function as followers.

    So, it means the employees in any company shape it. This is because they create and shape their leaders who in turn chart out their course of action.

    Employees who curry favour with their bosses will not create an
    ping new procedures for reviewing their safety, efficacy and quality.

    Professional from academic institutions, pharmaceutical industries, health care indust
    d shape the right type of leaders. This only follows logically.

    Robust followers, employees who are secure enough to not need to curry favour and behave sycophantly, feel at ease with their managers and are comfortable with their own independent thinking and
    y and representatives from various regulatory agencies are working out to design the regulatory requirements for manufacture and sale of combination products
    assertive behaviour. They engage in constructive debate and offer valuable feed back about their boss’ managerial style, broadening the manager’s conceptual perspective and sharpening his/her leadership skills.

    In addition, robust followers, can relate themse
    .

    As there is an increasing trend of the combination products companies manufacturing such products should be able to tackle the problems involved in the de
    lves and their roles to the ‘bigger picture’ of how the overall organization functions, and do not experience themselves as merely an isolated cog in a lone wheel.

    The spirit of a true champion should be championed for at our workplaces. Champions do not prop
    elopment. They need to be wiser in analyzing the market trends and the regulatory requirements.

    Companies that provide selfless information through particip
    ose to be considered as champions. What they do does the talking for them.

    The once lily-white fabric of the conventional workplace aura should be allowed to start gleaming and shining once more instead of dilly-dallying and wasting time in fruitless pursuits


    tion in industry events and feedback to regulatory authorities would be able to face the challenges and will be successful in developing combination products

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