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    Recently I shared with my readers a quote from Eleanor Roosevelt, who said: "Do one thing every day that scares you." I asked you to send me your stories about doing something that scared y
    According to USFDA, a combination product is one composed of any combination of a drug and device; biological product and device; drug and biological product
    ou in the service of your own progress and growth.

    I got some great responses and want to share one that touched on an issue that is nearly universal: how to deal with conflict constructiv
    ; or drug, device, and biological product and fixed dose combination would include two or more combinations of drug.

    Examples of combination products may in
    ely.

    This reader wrote that after reading the quote and invitation, she gathered her courage and spoke to a friend whose behavior had been intimidating her for a long time. It ended up bei
    lude drug-coated devices, drugs packaged with delivery devices in medical kits, and drugs and devices packaged separately but intended to be used together.

    g a productive conversation and she and her friend got back on track. Afterward, she thanked me for helping her realize she had the power in her own hands. She faced her fears and acted in
    here is enormous increase in the number of combination products entering the market in the recent years. Combination products have proven advantages but fixe
    spite of them.

    A common issue in working with my coaching clients is how to talk with someone about a problem – whether it is about a disagreement you are in the midst of, or it is about a
    d dose combinations are still in the process of convincing regulatory authority on their advantages over the single ingredient formulations.

    Combination pro
    agreement they broke with you.

    I recommend to my clients the books Crucial Conversations and Crucial Confrontations both by Patterson, Grenny, McMillan and Switzler. These are excellent b
    ucts have become life saving products for the pharmaceutical companies who doesn’t have many innovative molecules in their product pipeline and have been inc
    ooks based on over 25 years of studying 20,000 people who had learned to be masterful communicators through their own trial and error.

    Here are a couple of key suggestions from the books t
    easingly used in the product life cycle management. Even the companies having product patents are trying to extend their product life cycle through the combi
    o keep in mind:

    1. Start by creating safety by confirming mutual purpose and mutual respect. Mutual purpose means you both are working toward a common goal, such as growing a great company
    nation products and maximize the revenues. But the companies involved in this practice are overlooking that they are burdening the patients both economically
    or coming up with the best sales promotion.

    Mutual respect applies, as well, even if you have different opinions about the situation. If people feel that you don't respect them, it's impos
    and physically. They need to rightly judge the benefits of the combination products and they have to even look at the risks involved when combining the produ
    sible to have a productive conversation. They will start to defend their dignity.

    2. Avoid what is called the "fundamental attribution error" (what a mouthful!) where you decide the reason
    ts. Some of the combination products were well accepted by physicians while others suffered. Companies involved in development of combination products are fi
    someone is acting they way they are is because of a permanent character flaw, rather than situational reasons. Better to assume this person has good reasons for acting the way they are by a
    ding difficulty in defining their combination products and facing various challenges from selecting a combination to marketing it.

    Following aspects would a
    sking yourself: "Why would a rational, reasonable person be acting this way?" Better yet, talk to the person and don't assume you know why they are acting (or have acted) the way they are.
    dd to the challenges in developing combination products:

    Which markets to tap where the combination products can do fairly well?
    Which combination prod

    3. Use nonjudgmental, factual language that is based on observable facts. We often confuse our story with the facts. The authors ask you to ask yourself: "Can you see or hear this thing yo
    cts are meaningful and rational?
    Which therapeutic categories to select?
    Which Combinations can address unmet needs of the patients?
    Do combin
    're calling a fact? Was it an actual behavior?" Example:

    Fact: Your co-presenter gave 95% of the presentation and answered all but one question. Story: Your co-presenter doesn't trust you.
    tions increase the patient compliance?
    What would be the developing cost?
    How to tackle the risks encountered during combination product developmen


    Conclusions are subjective, so be careful with your language and also see the next tip.

    4. Use tentative language: "It sounds like perhaps…" I'm starting to wonder if…" "I've noticed som
    t?

    As combination products don't fit into the traditional categories of drugs, medical devices, or biological products, the USFDA is in the process of devel
    thing that seems like…" "I know this is probably not true, but…" This is not being timid; rather it helps prevent a strong reaction in the other person. When we use strong black or white la
    ping new procedures for reviewing their safety, efficacy and quality.

    Professional from academic institutions, pharmaceutical industries, health care indust
    nguage, we can usually count on a strong reaction back.

    Check out these books for a lot more guidance on skillfully handling challenging conversations. But whatever you do, don't avoid cha
    y and representatives from various regulatory agencies are working out to design the regulatory requirements for manufacture and sale of combination products
    llenging situations for too long. As with my subscriber who emailed in, you have business and personal relationships which depend on your doing just that. At the heart of successful busines
    .

    As there is an increasing trend of the combination products companies manufacturing such products should be able to tackle the problems involved in the de
    is great communication.

    The only way to get great at communication is to practice! That includes stumbling along the way, but like any skill, you do get better. So whether something happe
    elopment. They need to be wiser in analyzing the market trends and the regulatory requirements.

    Companies that provide selfless information through particip
    ned a long time ago or you're in the midst of it right now, gather your courage, take some new skills, and practice. You have only your limitations to lose and amazing breakthroughs to gain


    tion in industry events and feedback to regulatory authorities would be able to face the challenges and will be successful in developing combination products

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