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If you’ve been to the supermarket recently, chances are you’ve seen them: the new packaging methods being used to house products that used to only appear in

According to USFDA, a combination product is one composed of any combination of a drug and device; biological product and device; drug and biological product

cans. The grocery store has never seen so much innovation!

Where once they could only use cans, in recent years manufacturers of products like tuna fish, pe

; or drug, device, and biological product and fixed dose combination would include two or more combinations of drug.

Examples of combination products may in

t food, and nuts have taken the initiative to look at new types of packaging. These methods not only make their product more appealing to consumers, but also

lude drug-coated devices, drugs packaged with delivery devices in medical kits, and drugs and devices packaged separately but intended to be used together.

make it all-around better.

Jessica Simpson may have breathed new life into the Chicken of the Sea® brand, but even she couldn’t outdo the benefits of retor

here is enormous increase in the number of combination products entering the market in the recent years. Combination products have proven advantages but fixe

flexible packaging, a special pouch that uses steam or super-heated water to pre-cook food in its own package. Thanks to flexible packaging, manufacturers a

d dose combinations are still in the process of convincing regulatory authority on their advantages over the single ingredient formulations.

Combination pro

re finding new and exciting ways to market their products. Here is a brief list of just some of the ways retort flexible packaging have revolutionized the on

ucts have become life saving products for the pharmaceutical companies who doesn’t have many innovative molecules in their product pipeline and have been inc

ce-tired food-in-a-can industry:

1. Retort technology means food is pre-cooked, needing little (if any) additional preparation. And for those consumers that

easingly used in the product life cycle management. Even the companies having product patents are trying to extend their product life cycle through the combi

appreciate convenience, the less cooking, the better!

2. Today’s consumers demand convenience, so the flexible retort pouch is appealing because it can be r

nation products and maximize the revenues. But the companies involved in this practice are overlooking that they are burdening the patients both economically

e-sealed. Someone who opens a can of tuna and prepares half of it must then find a way to store what remains. With a re-sealable zip seal pouch, there’s no n

and physically. They need to rightly judge the benefits of the combination products and they have to even look at the risks involved when combining the produ

eed for other storage methods!

3. Believe it or not, retort technology makes food taste better. Here, food is spread out evenly, so it cooks faster than in

ts. Some of the combination products were well accepted by physicians while others suffered. Companies involved in development of combination products are fi

can. In cans, product at the edges can overcook, while product in the center can undercook. This problem is eliminated by the flexible pouch.

4. Flexible r

ding difficulty in defining their combination products and facing various challenges from selecting a combination to marketing it.

Following aspects would a

etort pouches are longer and wider than cans, so space for your brand message is increased. You can use graphic designs to catch consumers’ attention.

5. Th

dd to the challenges in developing combination products:

Which markets to tap where the combination products can do fairly well?
Which combination prod

e pouches’ unique construction (usually high-grade plastic, aluminum, or a blend of the two) take well to high-tech printing methods – so your artwork will r

cts are meaningful and rational?
Which therapeutic categories to select?
Which Combinations can address unmet needs of the patients?
Do combin

eally stand out at retail.

6. Retort flexible pouches can be made to stand up on retail shelves, or hang in a peg display, which increases your merchandisin

tions increase the patient compliance?
What would be the developing cost?
How to tackle the risks encountered during combination product developmen

opportunities.

7. What is one of the biggest complaints consumers have about cans? Sharp edges, of course! With retort flexible pouches, this problem is co

t?

As combination products don't fit into the traditional categories of drugs, medical devices, or biological products, the USFDA is in the process of devel

mpletely eliminated.

8. Before packages are filled, they can be stored flat, unlike cans. With warehouse space usually at a premium, this can free up a lot

ping new procedures for reviewing their safety, efficacy and quality.

Professional from academic institutions, pharmaceutical industries, health care indust

of room, and make for very happy warehouse managers.

9. Retort packages weigh less than cans, so you’ll save money on transportation and shipping.

10. Most

y and representatives from various regulatory agencies are working out to design the regulatory requirements for manufacture and sale of combination products

people think cans are more durable. Actually, retort flexible pouches are because they are made of several different high-quality layers that offer superior

.

As there is an increasing trend of the combination products companies manufacturing such products should be able to tackle the problems involved in the de

strength and resiliency. No dents here!

In closing, retort pouches continue to gain popularity along with other styles of flexible packaging such as standup

elopment. They need to be wiser in analyzing the market trends and the regulatory requirements.

Companies that provide selfless information through particip

pouches and barrier bags. While using cans may be a thing of the past, retort pouches and other types of flexible packaging are certain to be in our future

tion in industry events and feedback to regulatory authorities would be able to face the challenges and will be successful in developing combination products

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