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Packaging insiders all agree that for manufacturers who ship their products, plastic corrugated containers are the way to go. Because they are extremely durable, they can

According to USFDA, a combination product is one composed of any combination of a drug and device; biological product and device; drug and biological product

be re-used and returned over and over again, saving your company a lot of money in the process. But simply using corrugated plastic is not the only way you can save mone

; or drug, device, and biological product and fixed dose combination would include two or more combinations of drug.

Examples of combination products may in

. Before placing an order for plastic corrugated containers, consider the following ways to save even more:

1. Try different corrugated plastic container styles. Before

lude drug-coated devices, drugs packaged with delivery devices in medical kits, and drugs and devices packaged separately but intended to be used together.

urchasing a quantity of plastic corrugated containers, check to make sure the product you are looking at has all of the features you need. Ask your packaging producer for

here is enormous increase in the number of combination products entering the market in the recent years. Combination products have proven advantages but fixe

samples to try them out – catalogs cannot always give you the best idea of how a product will meet your specific needs.

2. Experiment with different thicknesses of corr

d dose combinations are still in the process of convincing regulatory authority on their advantages over the single ingredient formulations.

Combination pro

gated plastic containers. Plastic corrugated is available in a wide range of thicknesses: from 2mm to 13mm. If your application calls for it, a thinner plastic may be mor

ucts have become life saving products for the pharmaceutical companies who doesn’t have many innovative molecules in their product pipeline and have been inc

appropriate (and less expensive).

3. Check with your supplier to see if they have any plastic corrugated containers already in stock. Sometimes, your supplier may have

easingly used in the product life cycle management. Even the companies having product patents are trying to extend their product life cycle through the combi

some of this returnable packaging already (perhaps from an overrun or return).

4. Even if your supplier doesn’t have plastic corrugated containers already in stock, they

nation products and maximize the revenues. But the companies involved in this practice are overlooking that they are burdening the patients both economically

may have the corrugated plastic sheets available that are used to make containers. Depending on whether or not the size and thickness of the sheeting is right for you, yo

and physically. They need to rightly judge the benefits of the combination products and they have to even look at the risks involved when combining the produ

may be able to save by using raw materials your supplier already has.

5. Ask your supplier to run custom sheet sizes of corrugated plastic for your containers. If you u

ts. Some of the combination products were well accepted by physicians while others suffered. Companies involved in development of combination products are fi

e stock sheets that are not the right dimensions for your containers, you run the risk of accruing additional costs from having to die-cut the stock sheets, thus having e

ding difficulty in defining their combination products and facing various challenges from selecting a combination to marketing it.

Following aspects would a

xcess scrap.

6. Instead of custom printing your plastic corrugated containers, apply a printed label. A custom printed label that is then placed on your returnable conta

dd to the challenges in developing combination products:

Which markets to tap where the combination products can do fairly well?
Which combination prod

ner can look just as nice, and may last longer because it will not wear as quickly.

7. Ask if utility-grade plastic corrugated material is available. Made from recycled

cts are meaningful and rational?
Which therapeutic categories to select?
Which Combinations can address unmet needs of the patients?
Do combin

aterials, utility-grade corrugated plastic is less expensive than virgin material.

8. If using plastic corrugated for internal custom dunnage such as partitions, make th

tions increase the patient compliance?
What would be the developing cost?
How to tackle the risks encountered during combination product developmen

em last longer by having the pieces rod-locked so they will not come apart. Dividers constructed this way last longer because they are more protected against damage.

9.

t?

As combination products don't fit into the traditional categories of drugs, medical devices, or biological products, the USFDA is in the process of devel

lastic corrugated is naturally non-abrasive, but make sure to check how your product will react to it. If your product is susceptible to scratching or damage, it is bette

ping new procedures for reviewing their safety, efficacy and quality.

Professional from academic institutions, pharmaceutical industries, health care indust

to find out before you purchase the returnable packaging rather than after.

10. If your product is prone to scratching, have your plastic corrugated containers pre-trea

y and representatives from various regulatory agencies are working out to design the regulatory requirements for manufacture and sale of combination products

ted with a non-abrasive coating, such as spunbond fabric or cross-link foam. This way, your products will be protected and you will not have to worry about replacing or r

.

As there is an increasing trend of the combination products companies manufacturing such products should be able to tackle the problems involved in the de

pairing them once they arrive.

In closing, returnable packaging made from corrugated plastic is an ideal way to protect your product while reducing your packaging and sh

elopment. They need to be wiser in analyzing the market trends and the regulatory requirements.

Companies that provide selfless information through particip

pping costs. Don’t forget to consult with your packaging producer for guidance and direction; they’ll be able to design the best solution for your particular application

tion in industry events and feedback to regulatory authorities would be able to face the challenges and will be successful in developing combination products

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