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No matter the industry, there has always been conflict in the supply chain. That, I believe, will continue to be true. More t

According to USFDA, a combination product is one composed of any combination of a drug and device; biological product and device; drug and biological product

imes than I can remember, I have presented my keynote presentation titled, The New Era of Manufacturer/Distributor Coopera

; or drug, device, and biological product and fixed dose combination would include two or more combinations of drug.

Examples of combination products may in

tion at either manufacturing or distribution association meetings. In doing my research for these presentations, the supp

lude drug-coated devices, drugs packaged with delivery devices in medical kits, and drugs and devices packaged separately but intended to be used together.

y chain partners usually claim that they communicate well with each other. Unfortunately, that rarely proves to be the case.

here is enormous increase in the number of combination products entering the market in the recent years. Combination products have proven advantages but fixe

Through collaborative relationships, supply chain partners can improve.

In building an effective collaborative relationship

d dose combinations are still in the process of convincing regulatory authority on their advantages over the single ingredient formulations.

Combination pro

ith your supply chain partner the one thing that will help you the most to improve communication is your ability to understan

ucts have become life saving products for the pharmaceutical companies who doesn’t have many innovative molecules in their product pipeline and have been inc

d the value your supply chain partner needs to receive from the relationship. As an example, your procurement department migh

easingly used in the product life cycle management. Even the companies having product patents are trying to extend their product life cycle through the combi

believe that your supply partner should cut their price so low that they no longer make a profit. This is simply crazy.

If

nation products and maximize the revenues. But the companies involved in this practice are overlooking that they are burdening the patients both economically

you make an effort to understand the total value your supply partner needs and help them to receive that total value package,

and physically. They need to rightly judge the benefits of the combination products and they have to even look at the risks involved when combining the produ

they will perceive you as a great partner and communication will become easier. I am not suggesting that you give away the ba

ts. Some of the combination products were well accepted by physicians while others suffered. Companies involved in development of combination products are fi

nk, but rather only put your energies into activities, services, and so forth that delivers the value to your supply partner

ding difficulty in defining their combination products and facing various challenges from selecting a combination to marketing it.

Following aspects would a

that they want.

Supply Chain Improvements

Just-in-time inventory purchasing and supplying as exemplified by t

dd to the challenges in developing combination products:

Which markets to tap where the combination products can do fairly well?
Which combination prod

e famous relationship between Wal-Mart and Procter & Gamble has continued to prove successful. Home Depot and Dell Computers

cts are meaningful and rational?
Which therapeutic categories to select?
Which Combinations can address unmet needs of the patients?
Do combin

have also built powerful alliances with their suppliers for cost saving just-in-time inventory in similar applications. You

tions increase the patient compliance?
What would be the developing cost?
How to tackle the risks encountered during combination product developmen

an do this too. You can develop closer relationships with your supply chain partners.

Below are additional supply chain impr

t?

As combination products don't fit into the traditional categories of drugs, medical devices, or biological products, the USFDA is in the process of devel

ovement areas available to you through strategic alliance relationships:

1. Management of supply channel conflict

2. On-tim

ping new procedures for reviewing their safety, efficacy and quality.

Professional from academic institutions, pharmaceutical industries, health care indust

product delivery

3. Prompt response to complaints

4. Greater consistency in parts, supplies, semi-assembled, and completed

y and representatives from various regulatory agencies are working out to design the regulatory requirements for manufacture and sale of combination products

products

5. Detailed agreement as to handling of product problems and customer complaints

6. Improved supply chain product

.

As there is an increasing trend of the combination products companies manufacturing such products should be able to tackle the problems involved in the de

vity

7. Specific (quarterly, yearly, etc.) volume commitments

8. Key contacts that are dedicated to your account

9. Improv

elopment. They need to be wiser in analyzing the market trends and the regulatory requirements.

Companies that provide selfless information through particip

ed supplier loyalty

10. Prompt response to quote requests and price problems

11. Confidentiality of shared business strateg

tion in industry events and feedback to regulatory authorities would be able to face the challenges and will be successful in developing combination products

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