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If you have ever been to a seaport it is a busy place with heavy cranes and material handling equipment everywhere. Containers lined up sometimes 6-8 high, it is a scary place for some bu

According to USFDA, a combination product is one composed of any combination of a drug and device; biological product and device; drug and biological product

t for a material handling equipment supply and services company it is a dream come true. The seaports only job is to move freight to and from our shores. America exports all kinds of good

; or drug, device, and biological product and fixed dose combination would include two or more combinations of drug.

Examples of combination products may in

and imports every thing from car parts to computers.

Those containers represent World Trade, US trade deficit and the hopeful economies of many third world nations busy trying to fulfil

lude drug-coated devices, drugs packaged with delivery devices in medical kits, and drugs and devices packaged separately but intended to be used together.

the needs of our economic powerhouse and strong middle class base. This is why a material handling equipment and supply services company salesman is in heaven near such waters. But on my

here is enormous increase in the number of combination products entering the market in the recent years. Combination products have proven advantages but fixe

last visit I spent some time in a coffee shop with a container specialist who later switched jobs and became a material handling equipment supply guy. He told me he sold everything you co

d dose combinations are still in the process of convincing regulatory authority on their advantages over the single ingredient formulations.

Combination pro

ld ever think of that was used in any part of the shipping business, from plastic wrap machines for small business to shock mats for the inside of trucks and cargo containers to protect t

ucts have become life saving products for the pharmaceutical companies who doesn’t have many innovative molecules in their product pipeline and have been inc

e cargo, freight and exported goods to foreign shores.

I asked him about lighting and he said yes our company has manufactured lines on that too, he then asked me; “How many lights do yo

easingly used in the product life cycle management. Even the companies having product patents are trying to extend their product life cycle through the combi

need and when do you want them?” What a salesmen, so since I was not actually buying lights, I bought him a cup of coffee to pick his brain. I asked him how do they light up such large S

nation products and maximize the revenues. But the companies involved in this practice are overlooking that they are burdening the patients both economically

aports and do you have an energy efficient lighting that uses no power source? He said; “Oh, we have all types of energy efficient bright lights that can light up a stadium, how many do y

and physically. They need to rightly judge the benefits of the combination products and they have to even look at the risks involved when combining the produ

u need?” I enjoyed his assertive “trial close” sales tactics, he must have went to Ziggy Ziglar’s Sales Seminars? Not bad I thought for a material handling equipment and supply specialist

ts. Some of the combination products were well accepted by physicians while others suffered. Companies involved in development of combination products are fi

and consultant, who would have thought? As we talked it was apparent that no one uses solar panels to light up the seaports, they do not use wind, they bite the bullet and work of the pow

ding difficulty in defining their combination products and facing various challenges from selecting a combination to marketing it.

Following aspects would a

r grid. He had no system that does not “plug in” in the way of lighting. They don’t exist.

I therefore propose using all the vibrational energy from the cranes, clanking of containers, f

dd to the challenges in developing combination products:

Which markets to tap where the combination products can do fairly well?
Which combination prod

rklifts, ship motors and material handling equipment to power up the lights at the modern seaport. How so you ask? Well, let me tell you what I told the material handling supply and equip

cts are meaningful and rational?
Which therapeutic categories to select?
Which Combinations can address unmet needs of the patients?
Do combin

ent consultant. You see, by placing large sandwich sheets around the port where you want the light, which are specially designed with a taunt film on the vibrational side and small copper

tions increase the patient compliance?
What would be the developing cost?
How to tackle the risks encountered during combination product developmen

lined tubes, hundreds of them running perpendicular to the sheets, with magnets inside bouncing back and forth. These magnets will charge a capacitor and be hooked up to an LED lighting s

t?

As combination products don't fit into the traditional categories of drugs, medical devices, or biological products, the USFDA is in the process of devel

stem using fiber optics or reflectors, each one hooked up to a .2 to .5 watt light. With hundreds of thousands of lights hooked up in a composite format it will light up the roadways and

ping new procedures for reviewing their safety, efficacy and quality.

Professional from academic institutions, pharmaceutical industries, health care indust

eaport storage yards and since the lights can shine down on the yards marked roads it would be like daylight without the light pollution associated with street lights in large ports, yet

y and representatives from various regulatory agencies are working out to design the regulatory requirements for manufacture and sale of combination products

he same or better light for those working. We must have proper lighting at our seaports for security in case the power goes out.

Currently this technology is being used in those little f

.

As there is an increasing trend of the combination products companies manufacturing such products should be able to tackle the problems involved in the de

ashlights you see advertised on television that you shake and they light, but you never need batteries. This idea of lighting up the Seaports is using that technology on a larger scale wi

elopment. They need to be wiser in analyzing the market trends and the regulatory requirements.

Companies that provide selfless information through particip

h miniaturized parts making up the guts between the sandwich sheets. Let there be light, thru vibrational energy and there was, the whole seaport lit up like a Christmas Tree. Think on it

tion in industry events and feedback to regulatory authorities would be able to face the challenges and will be successful in developing combination products

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