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Henry Ford knew a thing or two about inventions. Although he had very little formal education, there were those who calle

According to USFDA, a combination product is one composed of any combination of a drug and device; biological product and device; drug and biological product

d him a genius (they meant an invention genius).

So there is a lot any inventor can learn from the life of Henry Ford th

; or drug, device, and biological product and fixed dose combination would include two or more combinations of drug.

Examples of combination products may in

at can end up being pretty useful, even today.

A) An inventor Must Have A Vision
Henry Ford dreamed of revol

lude drug-coated devices, drugs packaged with delivery devices in medical kits, and drugs and devices packaged separately but intended to be used together.

tionizing the life of the ordinary American by opening up the countryside for them with his invention. The motor vehicle

here is enormous increase in the number of combination products entering the market in the recent years. Combination products have proven advantages but fixe

he had in mind was more than just a mode of transportation. A clear vision can overcome many obstacles and keep you going

d dose combinations are still in the process of convincing regulatory authority on their advantages over the single ingredient formulations.

Combination pro

against great odds.

People often laughed at Ford and some thought that he was crazy. His boss at an electric company onc

ucts have become life saving products for the pharmaceutical companies who doesn’t have many innovative molecules in their product pipeline and have been inc

e offered him a big raise to “stop fooling around with those petrol engines.”

Luckily Henry Ford knew that a vision was

easingly used in the product life cycle management. Even the companies having product patents are trying to extend their product life cycle through the combi

more important than a big raise and more important than all the money in the world. The Ford fortune and the company he f

nation products and maximize the revenues. But the companies involved in this practice are overlooking that they are burdening the patients both economically

unded on his invention and the ideas you are reading about in this article are still in existence. Both will outlive the

and physically. They need to rightly judge the benefits of the combination products and they have to even look at the risks involved when combining the produ

man by several hundred years.

Many times as you wait for the product to enter the market your vision will be all you hav

ts. Some of the combination products were well accepted by physicians while others suffered. Companies involved in development of combination products are fi

as an inventor. A vision is critical so dream away, but make sure that it is more than a dream by doing something about

ding difficulty in defining their combination products and facing various challenges from selecting a combination to marketing it.

Following aspects would a

it.

B) If Your Invention Is Good Enough The Market Will Always Finance It
Even in the days of Henry Ford “se

dd to the challenges in developing combination products:

Which markets to tap where the combination products can do fairly well?
Which combination prod

nsible educated people” believed that you would never bring an invention to the market without a fortune in capital. Henr

cts are meaningful and rational?
Which therapeutic categories to select?
Which Combinations can address unmet needs of the patients?
Do combin

Ford believed that if you had a product, you made a cheap prototype and if it was good enough, it would find customers w

tions increase the patient compliance?
What would be the developing cost?
How to tackle the risks encountered during combination product developmen

ho would finance every aspect of its production. You sold one unit and it financed you to manufacture a couple more until

t?

As combination products don't fit into the traditional categories of drugs, medical devices, or biological products, the USFDA is in the process of devel

you had a business going. This was in sharp contrast to the situation that Ford said he saw often where bankers put a for

ping new procedures for reviewing their safety, efficacy and quality.

Professional from academic institutions, pharmaceutical industries, health care indust

tune in a business that was a bad idea and when inevitably it did not make a profit, even more money was pumped in.

Ford

y and representatives from various regulatory agencies are working out to design the regulatory requirements for manufacture and sale of combination products

went ahead and proved what he was saying was correct with his own Ford Motor Company which never took out a bank loan in

.

As there is an increasing trend of the combination products companies manufacturing such products should be able to tackle the problems involved in the de

an industry that has traditionally required heavy financing to this day.

So, no matter what people say, put out of your

elopment. They need to be wiser in analyzing the market trends and the regulatory requirements.

Companies that provide selfless information through particip

mind the fact that you do not have the big capital required to launch your invention and instead do it the Henry Ford way

tion in industry events and feedback to regulatory authorities would be able to face the challenges and will be successful in developing combination products

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