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    All larger companies and all those who have been in the market for several business cycles are prone
    According to USFDA, a combination product is one composed of any combination of a drug and device; biological product and device; drug and biological product
    to an (identity) crisis. Corporate identity and the product of the company are related. This is qui
    ; or drug, device, and biological product and fixed dose combination would include two or more combinations of drug.

    Examples of combination products may in
    te important when dealing with change.

    In his book – “let’s make things better,” Marcel Metze write
    lude drug-coated devices, drugs packaged with delivery devices in medical kits, and drugs and devices packaged separately but intended to be used together.

    s about the Philips culture which is centered around engineers on one side and salesmen on the other
    here is enormous increase in the number of combination products entering the market in the recent years. Combination products have proven advantages but fixe
    ; some how these two groups keep the organization in balance.

    For those of you how know Philips kno
    d dose combinations are still in the process of convincing regulatory authority on their advantages over the single ingredient formulations.

    Combination pro
    w that this company “makes things,” it operates in consumer electronics, appliances, medical systems
    ucts have become life saving products for the pharmaceutical companies who doesn’t have many innovative molecules in their product pipeline and have been inc
    or in general in a wide area of products that require a design (which is sales centered) and engine
    easingly used in the product life cycle management. Even the companies having product patents are trying to extend their product life cycle through the combi
    ering (which is product centered).

    Philips is a company that is more than hundred years old and has
    nation products and maximize the revenues. But the companies involved in this practice are overlooking that they are burdening the patients both economically
    survived many crises. Currently ABN AMRO is struggling with some kind of a crisis. One of the prob
    and physically. They need to rightly judge the benefits of the combination products and they have to even look at the risks involved when combining the produ
    lems the company is dealing with is that it is too large for the Netherlands and too small to be a w
    ts. Some of the combination products were well accepted by physicians while others suffered. Companies involved in development of combination products are fi
    orld player.

    There is a big difference however between both companies. One (Philips) is a producer
    ding difficulty in defining their combination products and facing various challenges from selecting a combination to marketing it.

    Following aspects would a
    and ABN AMRO a financial institution, a bank. Cultural-wise both companies are of course quite diff
    dd to the challenges in developing combination products:

    Which markets to tap where the combination products can do fairly well?
    Which combination prod
    erent too. Where a producers’ culture is strongly based on a tangible product with which employees c
    cts are meaningful and rational?
    Which therapeutic categories to select?
    Which Combinations can address unmet needs of the patients?
    Do combin
    an identity themselves easily, a financial company lacks such a tangible product and requires more e
    tions increase the patient compliance?
    What would be the developing cost?
    How to tackle the risks encountered during combination product developmen
    ffort to build a cultural identity. This makes that a financial company should invest more in cultur
    t?

    As combination products don't fit into the traditional categories of drugs, medical devices, or biological products, the USFDA is in the process of devel
    e where much of the culture of a production company comes with the “nature” of this product itself.
    ping new procedures for reviewing their safety, efficacy and quality.

    Professional from academic institutions, pharmaceutical industries, health care indust

    Companies that are dealing with a shift from a product-oriented culture to a service-oriented cultu
    y and representatives from various regulatory agencies are working out to design the regulatory requirements for manufacture and sale of combination products
    re struggle with this cultural element too.

    A good example of a company that has a strong identity
    .

    As there is an increasing trend of the combination products companies manufacturing such products should be able to tackle the problems involved in the de
    and is proud to show this to the external world is Seiko. Just have a look. It all seems to fit. Suc
    elopment. They need to be wiser in analyzing the market trends and the regulatory requirements.

    Companies that provide selfless information through particip
    h a company will be around for “ever:” www.sii.co.jp/corp/eg/company/company7.html

    © 2007 Hans Boo


    tion in industry events and feedback to regulatory authorities would be able to face the challenges and will be successful in developing combination products

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